George C. ScottLt. William 'Bill' Kinderman

Ed FlandersFather Joseph Kevin Dyer

Brad DourifJames Venamun / The Gemini Killer

Jason MillerFather Damien Karras / Patient X

Nicol WilliamsonFather Morning

Scott WilsonDr. Temple

Nancy FishNurse Allerton

George DiCenzoStedman

Don GordonRyan

Lee RichardsonUniversity President

Grand L. BushSergeant Atkins

Mary JacksonMrs. Clelia

Viveca LindforsNurse X

Ken LernerDr. Freedman

Tracy ThorneNurse Keating

Barbara BaxleyShirley

Zohra LampertMary Kinderman

Harry Carey, Jr.Father Kanavan

Sherrie WillsJulie Kinderman

Edward LynchPatient A

Clifford DavidDr. Bruno

Alex ZuckermanKorner Boy

Lois ForakerNurse Merrin

Tyra FerrellNurse Blaine

James BurgessThomas Kintry

Kevin CorriganAltar Boy

Peggy AlstonMrs. Kintry

John DurkinElderly Jesuit

Bobby DerenNurse Bierce

Jan NeubergerAlice

Alexis ChieffetCounter Attendant

Debra PortWaitress

Walt MacPhersonPolice Sergeant

David DwyerSecond Police Officer

Danny EpperPolice Driver

William PrestonOld Man in Wheelchair

Chuck KinlawAttendant

Demetrios PappageorgeCasperelii

Nina HansenLittle Old Lady

Samuel L. JacksonDream Blind Man

Jan SmookRadio Man

Amelia CampbellYoung Girl in Dream

Cherie BaronNurse

Larry KingLarry King

C. Everett KoopEverett Koop

Patrick EwingAngel of Death

Charles Edwin PowellPatient X Possessed

William Peter BlattyDirector & Screenplay

Carter DeHavenProducer

Joe RothExecutive Producer

James G. RobinsonExecutive Producer