Kyle MacLachlanDale Cooper

Michael HorseDeputy Tommy “Hawk” Hill

Al StrobelThe One Armed Man

Kimmy RobertsonLucy Moran

Harry GoazDeputy Andy Brennan

Sheryl LeeLaura Palmer / Maddy Ferguson

Dana AshbrookRobert "Bobby" Briggs

Mädchen AmickShelly Johnson

Piper LaurieCatherine Martell

Russ TamblynDr. Lawrence Jacoby

Peggy LiptonNorma Jennings

James MarshallJames Hurley

Sherilyn FennAudrey Horne

Ray WiseLeland Palmer

Everett McGillBig Ed Hurley

Warren FrostDr. Will Hayward

Jack NancePete Martell

Joan ChenJocelyn 'Josie' Packard

Michael OntkeanSheriff Harry S. Truman

Richard BeymerBenjamin 'Ben' Horne

Lara Flynn BoyleDonna Hayward

Wendy RobieNadine Hurley

Miguel FerrerFBI Agent Albert Rosenfield

Catherine E. CoulsonMargaret Lanterman / The Log Lady

Don S. DavisMajor Garland Briggs

Frank SilvaBob

Eric DaReLeo Johnson

Chris MulkeyHank Jennings

Ian BuchananDick Tremayne

David Patrick KellyJerry Horne

Alicia WittGersten Hayward

Chrysta BellFBI Agent Tammy Preston

Robert ForsterSheriff Frank Truman

Naomi WattsJaney-E Jones

Kenneth WelshWindom Earle

Carel StruyckenThe Giant

Charlotte StewartBetty Briggs

Pierce GagnonSonny Jim Jones

Laura DernDiane Evans

John BoylanDwayne Milford

John PirruccelloDeputy Chad Broxford

Don MurrayBushnell Mullins

Brent BriscoeDetective Dave Macklay

Dan O'HerlihyAndrew Packard

Robyn Lively

Heather GrahamAnnie Blackburn

Victoria CatlinBlackie O'Reilly

Walter OlkewiczJacques Renault

Jane AdamsConstance Talbot

Tom SizemoreAnthony Sinclair

Patrick FischlerDuncan Todd

Phoebe AugustineRonette Pulaski

Jennifer Jason LeighChantal Hutchens

Eamon FarrenRichard Horne

Jim BelushiBradley Mitchum

Robert KnepperRodney Mitchum

Amy ShielsCandie

Giselle DaMierSandie

Andréa LealMandie

Brenda Strong

James Booth

Michael ParksJean Renault

Don AmendoliaEmory Battis

George GriffithRay Monroe

Lance DavisChet

Jan D'ArcySylvia Horne

James MorrisonWarden Dwight Murphy

Harry Dean StantonCarl Rodd

Tim RothGary "Hutch" Hutchens

J.R. StarrMC

Gary HershbergerMike "Snake" Nelson

Billy ZaneJohn Justice Wheeler

Lenny Von DohlenHarold Smith

Hank WordenWaiter

Mary Jo DeschanelEileen Hayward

David DuchovnyDenise Bryson

Peter Michael GoetzJared

Mak TakanoAsian Man

Matthew LillardWilliam Hastings

Andrea HaysHeidi

Christophe Zajac-DenekIke "The Spike" Stadtler

Ashley JuddBeverly Paige

Sarah Jean LongMiriam Sullivan

David KoechnerDetective D. Fusco

Eric EdelsteinDetective "Smiley" Fusco

Larry ClarkeDetective T. Fusco

Amanda SeyfriedRebecca "Becky" Burnett

Josh FademPhil Bisby

Caleb Landry JonesSteven Burnett

Clark MiddletonCharlie

Jake WardleFreddie Sykes

Nae YuukiNaido

Jay R. FergusonSpecial Agent Randall Headley

Galyn GörgNancy

David L. Lander

David Warner

Jane Greer

Jill Rogosheske

Tony Jay

Robert BauerJohnny Horne

Erika AndersonEmerald / Jade

Rick GiolitoMontana

Hailey GatesDrugged-out Mother

Karl MakinenInspector Randy Hollister

Matt Battaglia

Erica EynonExperiment

Adele RenéLieutenant Cynthia Knox

David DastmalchianPit Boss Warrick

Balthazar GettyRed

James GrixoniDeputy Jesse Holcomb

Jodi ThelenMaggie

Linda PorterLady Slot-Addict

Joe AdlerRoger

Jessica SzohrRenee

Owain Rhys DaviesAgent Wilson

Jay AasengDrunk

Nathan FrizzellPhillip Jeffries (voice)

Julee CruiseSinger

Ritch BrinkleyD.A. Daryl Lodwick

David LynchCreator

Mark FrostCreator