Charlie TahanVictor Frankenstein (voice)

Catherine O'HaraMrs. Frankenstein / Weird Girl / Gym Teacher (voice)

Martin ShortMr. Frankenstein / Mr. Burgemeister / Nassor (voice)

Martin LandauMr. Rzykruski (voice)

Atticus ShafferEdgar "E" Gore (voice)

Winona RyderElsa Van Helsing (voice)

Robert CapronBob (voice)

James Hiroyuki LiaoToshiaki (voice)

Conchata FerrellBob's Mom (voice)

Tom KennyNew Holland Townsfolk (voice)

Frank WelkerSparky Frankenstein (voice)

Dee Bradley BakerPersephone van Helsing / Shelly / Were-Rat / Colossus

Jeff BennettGiant Sea Monkeys (voice)

Jon DonahueAdditional Voices (voice)

Tim BurtonDirector, Characters, Idea

John AugustScreenplay

Leonard RippsOriginal Story

Christian De VitaStoryboard

Jørgen KlubienStoryboard, Story Developer

Dean RobertsStoryboard

Philip VallentinStoryboard

Sharon SmithStoryboard

Gabriele ZucchelliStoryboard

Padraig CollinsStoryboard

Mary ShelleyOriginal Story

Don HahnExecutive Producer

Allison AbbateProducer